However, the result was heterogeneous; therefore, we are unable to make any implications from this. High‐dose alcohol decreased SBP by 3.49 mmHg within the first six hours, Drug rehabilitation and by 3.77 mmHg between 7 and 12 hours after consumption. After 13 hours, high doses of alcohol increased SBP by 3.7 mmHg compared to placebo.
Summary of findings 1. Effect of high‐dose alcohol compared to placebo .
The molecular mechanisms through which alcohol raises blood pressure are unclear. Alcohol can affect blood pressure through a variety of possible mechanisms. Previous research suggests that acute alcohol consumption affects the renin–angiotensin–aldosterone system (RAAS) by increasing plasma renin activity (Puddey 1985). The RAAS is responsible for maintaining the balance of fluid and electrolytes.

Berglund 1989 published data only
- Older adults — drinkers, nondrinkers, it doesn’t matter — are already at risk for hypertension.
- Alcohol consumption also presents risks for individuals with specific health conditions beyond high blood pressure.
- A high dose of alcohol typically raises your blood pressure for about 24 hours after you drink it.
- Buckman 2015, Van De Borne 1997, and Fazio 2001 also reported reduced baroreflex sensitivity following alcohol consumption.
As a result, we were not able to quantify the magnitude of the effects of alcohol on men and women separately. This is unfortunate, as we have reason to believe that the effects of alcohol on BP might be greater in women. In the case of registration at clinical trials.gov, we considered only one study to have low risk of bias (Barden 2013).
Stubbs 1995 published data only
Physical conditioning attenuates the chronic ethanol-induced hypertension by augmenting the NO bioavailability and reducing the oxidative stress response in rats19,79,108. Imbalance of specific endogenous vasoconstrictor such as angiotensin II, endothelin-1 and nor-epinephrine and vasodilator nitric oxide (NO) may also play an important role in alcohol-induced hypertension. Alcohol stimulates the release of endothelin 1 and 2 from vascular endothelium in a dose dependent manner81. Alcohol also increases the angiotensin II levels in the blood and vessels62,63. Endothelin 1 and 2 as well as angiotensin II are known to be potent vasoconstrictors of the blood vessels63,81.

This is the golden question, and I wish there were a one-size-fits-all answer. Typically, I tell my patients that blood pressure might remain elevated for a few days to a couple weeks post-withdrawal. But again—it varies wildly based on how much you were drinking, how long you’ve been doing it, and your baseline health. Heavy alcohol use may be one cause of treatment‐resistant hypertension, since alcohol may interfere with the pharmacologic action of antihypertensive agents.
Tresserra‐Rimbau 2013 published data only

It also helps regulate your nervous system and keep anxiety in check, which is often revved up during withdrawal. The goal is always long-term health, and sometimes that means short-term interventions. She and the lifestyle team cover a range of story topics including food and drink, travel, and health. Jones called the new alcohol guidance one of the two “most notable changes in the 2025 guidelines,” along with reducing sodium intake from 2300 mg a day to 1500 mg a day. “A lot of people enjoy drinking, but because the evidence is there, we want you to make an informed decision,” Jones said.
- All extracted data were entered and double‐checked in RevMan 5.3 software (Review Manager (RevMan)).
- High blood pressure (hypertension) is a major risk factor for heart disease and stroke, while extremely low blood pressure can also create immediate health concerns.
- A 2021 review found that in women, drinking even a moderate amount of alcohol can increase the risk of hypertension.
- Chan et al60 have proposed that expansion of the extracellular fluid is the result of elevated plasma vasopressin levels and plasma renin activity, indicating increased sympathetic stimulation.
Vijaya Musini (VM) contributed to data analysis, interpretation of the final result, and editing of the final draft of the review. James M Wright (JMW) formulated the idea, developed the basis of the protocol, and contributed to data analysis, interpretation of the final result, and editing of the final draft of the review. We excluded 450 trials after reviewing the full‐text articles, and we recorded the reasons for exclusion (see table Characteristics of excluded studies table). All outcomes of alcohol blood pressure interest in the review (BP and HR) produced continuous data. We calculated and reported mean difference (MD), with corresponding 95% confidence interval (95% CI). We included adult (≥ 18) participants of both sexes without any restriction on their health condition.
New MAHA dietary guidelines prioritize meat over plant based proteins
Even moderate alcohol consumption can be problematic if it causes harm to the drinker’s health and well-being. For instance, someone with high blood pressure may be at an increased risk of negative side effects due to drinking alcohol. Drinking too much can also trigger sleep problems and lead to weight gain, which can harm your blood pressure, heart health, and your whole body. Over time, heavy drinking also makes many other serious health problems more likely, including heart disease, heart failure, liver disease, alcohol use disorder, and certain types of cancer.
All extracted data were entered and double‐checked in RevMan 5.3 software (Review Manager (RevMan)). All randomised controlled trials (RCTs) that compared alcohol to placebo or similar tasting non‐alcoholic beverages were included in this systematic review. The new report released on August 14 highlights that both systolic and diastolic blood pressure tend to rise with continued alcohol use. Individuals who abstain from alcohol altogether were found to have the lowest risk of developing hypertension, while those who cut their alcohol intake by at least half showed significant improvements in blood pressure.
It is important to note that information regarding to the method of randomisation used in Foppa 2002 and Rosito 1999 was provided by the study author via email. Different types of alcoholic beverages including red wine, white wine, beer, and vodka were used among 32 studies. The dose of alcohol ranged between 0.35 mg/kg and 1.3 g/kg, and alcohol was consumed over five minutes and over one hour and 30 minutes. We are also moderately certain that high‐dose alcohol decreased blood pressure within six hours, and the effect lasted up to 12 hours.
Alcohol increases the risk of several other short- and long-term health issues. The unit of measurement for blood pressure is millimeters of mercury (mm Hg). Hypertension, or high blood pressure, is a very common condition worldwide. Kimberly Goad is a New York-based journalist who has covered health for some of the nation’s top consumer publications. Her work has appeared in Women’s Health, Men’s Health and Reader’s Digest.Dr.
In this study, alcohol had no significant effect on DBP in the four groups. We reviewed available evidence about the short‐term effects of different doses of alcoholic drinks compared to non‐alcoholic drinks on blood pressure and heart rate in adults (≥ 18 years) with both normal and raised blood pressure. To determine short‐term dose‐related effects of alcohol versus placebo on systolic blood pressure and diastolic blood pressure in healthy and hypertensive adults over 18 years of age. It is a common substance of abuse and its use can lead to more than 200 disorders including hypertension.
